The Numerical Analysis Council (CAN) of SFR BioSciences is organising a practical training course on differential expression analysis using bulk RNA-seq data.

The goal: master every step of the analysis process, from raw sequencing files to result interpretation, with no technical prerequisites.

This training is especially suited to participants who already have an RNA-seq dataset at hand, whether from public sources (e.g. published articles) or generated as part of their own research projects.

Key information

  • Dates: Tuesday and Thursday afternoons (1:30–5:00 pm), from 24 February to 31 March 2026 (10 sessions),
  • Location: training room at the ENS Monod site (subject to availability),
  • Language: training in French, materials in English,
  • Target audience: priority given to participants who already have an RNA-seq dataset or plan to generate one in the near future,
  • Format: free, limited to 15 participants, with a strong focus on hands-on practice (including 2 sessions dedicated to analysing your own data).

Registration

  • Deadline: 30 January 2026registration form,
  • Commitment: selected participants are expected to attend all sessions,
  • Selection: notification by the week of 2 February.

Programme

Part 1 — Raw data processing

  • Bash basics for RNA-seq data preprocessing,
  • Quality control of raw sequencing reads,
  • Cleaning and filtering low-quality reads,
  • Alignment/mapping of reads to the reference transcriptome,
  • Generation of count tables (per gene or transcript).

Part 2 — Statistical analysis with DESeq2

  • Differential expression analysis,
  • R basics for DESeq2 usage and plotting,
  • Exploration and visualisation of statistical results,
  • Functional enrichment analysis.

For any questions, feel free to contact Carine Rey.